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HIF-1 and mechanisms of hypoxia sensing

All genes were analyzed while correcting for five main cell-types for which the cell-type signal was estimated by taking the mean expression of markers: 628 neurons, 332 astrocytes, 186 oligodendrocytes, 520 microglia, and 456 endothelial cells

Prospective mechanisms include high-frequency patterns obscuring encoded information, suppression of abnormal beta oscillations, stimulation of inhibitory gamma-aminobutyric acid (GABAergic) afferents to the nucleus in focus, efferent projections or passing fibers, and the inhibition of neurotransmitter and hormone production or release

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